Ernesto Bertarelli

Inherited biotech firm Serono when father died in 1998. Ran for years; expanded revenue to $2.4 billion by 2006. Blockbuster drug: $1.4 billion (annual sales) multiple sclerosis therapy Rebif. Sold company to Germany's Merck in 2007 and took home $9 billion with his sister and mother. Avid sailor's Team Alinghi, two-time winner of the America's Cup, lost to rival racing billionaire Larry Ellison in hotly anticipated re-match in February 2010 after 30 months of legal wrangling. Bertarelli, who has five yachts, says he's done with the America's Cup though still plans to compete in more low-key events. Launched investment firm Ares Life Sciences 2008; investing $680 million in healthcare companies. Family supports ocean conservation. Married to former British beauty queen. Also a singer, she released her debut album 'Elusive' in early 2010, performed live at the Montreux Jazz Festival and did opening acts for Simply Red in Edinburgh and Zurich. .