Mundine was the National President of the Australian Labor Party (ALP), but quit the party in 2012. Mundine was appointed chairman of the Coalition government's Indigenous Advisory Council by then-prime minister, Tony Abbott. Mundine was the Liberal Party's unsuccessful candidate for the marginal seat of Gilmore on the south coast of New South Wales in the 2019 Australian federal election. Mundine maintained his interest in indigenous advocacy in his role with Andrew Forrest's Pilbara Mining indigenous charity Generation One. Abbott appointed Mundine chairman of the Australian government's Indigenous Advisory Council though this body was dissolved dissolved in 2017. He is an advocate for nuclear energy and, along with Jacinta Price, recently took a paid position with the Centre for Independent Studies as an advocate for indigenous issues but has maintained a strong climate denialist advocacy.