Negrin worked for Philadelphia District Attorney’s Office prosecuting hate crimes and violent crimes in the city. He eventually moved up to work in the Major Trials Unit. Negrin served as managing director and deputy mayor for the city of Philadelphia where he oversaw an annual budget of $5.5 billion. Negrin also oversaw the growth of PhillyRising, an innovative neighborhood quality-of-life initiative that utilizes technology to help create an improved sense of community and deliver vital services. Negrin also served as vice-chair of the independent Philadelphia Board of Ethics from 2006 to 2010. Negrin has worked as vice president and general counsel of ARAMARK’s Healthcare and Correctional Services Businesses, and as a partner at the law firm of Obermayer, Rebmann, Maxwell & Hippel.