O’Brien graduated from Bates in 1991 with a degree in economics and a secondary concentration in Russian language. O’Brien is the president, chief investment officer and principal owner of Promethean Investment Group, LLC, and affiliated private investment firms focused on institutional asset management and merchant banking. Before establishing Promethean, O’Brien was managing director in charge of strategic development and implementation for Fletcher Asset Management Inc. O’Brien began his professional career as a financial analyst in the Paper and Forest Products Group of the Corporate Finance Department at Salomon Brothers Inc. In Bates affairs, O’Brien has been active as a member of the Bates College New York Council and the New York Bates Business Network Steering Committee. In 1998, O’Brien named a Pettengill Hall history department office in honor of Thomas V. Keefe, his mother’s father. In 2002, O’Brien and his wife, Erika, created a scholarship fund with a preference for students from the metropolitan New York City area.