Senior Minister and former Prime Minister of the Republic of Singapore. The founding father and first prime minister of Singapore who transformed that tiny island outpost into one of the wealthiest and least corrupt countries in Asia. Mr. Lee was prime minister from 1959, when Singapore gained full self-government from the British, until 1990, when he stepped down. Late into his life he remained the dominant personality and driving force in what he called a First World oasis in a Third World region. Since Singapore separated from Malaysia in 1965 — an event Mr. Lee called his “moment of anguish” — he had seen himself in a never-ending struggle to overcome the nation’s lack of natural resources, a potentially hostile international environment and a volatile ethnic mix of Chinese, Malays and Indians. Lee Kuan Yew, who was sometimes known by his English name, Harry Lee, was born in Singapore on Sept. 16, 1923, to a fourth-generation, middle-class Chinese family. He worked as a translator and engaged in black market trading during the Japanese occupation in World War II, then went to Britain, where he earned a law degree in 1949 from Cambridge University. In 1950 he married Kwa Geok Choo, a fellow law student from Singapore. She died in 2010. After serving as prime minister from 1959 to 1990, Mr. Lee was followed by two handpicked successors, Goh Chok Tong and Mr. Lee’s eldest son, Lee Hsien Loong, who, groomed for the job, has been prime minister since 2004. Besides the prime minister, Mr. Lee is survived by his younger son, Lee Hsien Yang, who is the chairman of the Civil Aviation Authority of Singapore; a daughter, Dr. Lee Wei Ling, who runs the National Neuroscience Institute; a younger brother, Suan Yew; and a younger sister, Monica. Ho Ching, the wife of the prime minister, is executive director and chief executive of Temasek Holdings, a government holding company.