Fruit and real estate tycoon has lost $300 million in last 12 months, much of it going to Uncle Sam as he sells off pricey Hawaiian property. High school dropout drafted into Army 1943; settled in Detroit after WWII. Bought diner with $1,800 loan; flipped quickly for small profit. Built homes in Arizona, California; survived real estate market crash. Bought slice of Dole produce outfit, Castle & Cooke real estate firm. Dole sales up 10% in past 12 months despite rising food costs. Actively pursuing health and nutrition research since his third wife passed away from cancer in 1985. Expanding his $1.5 billion North Carolina Research Campus; studying biotech, disease, biorepository.