Nancy Lillian Buc, Esq., was born in Orange, New Jersey on July 27, 1944 to Ethel R. and George L. Buc. She has one living sibling, Lawrence G. Buc (Brown '68) and one deceased sibling, Vivian E. Buc. She grew up in West Orange, New Jersey, and the suburbs of Pittsburgh, Pennsylvania before moving to the Washington, DC area while in college. In the Pittsburgh suburbs, Buc attended public grade school and then the Upper St. Clair Junior-Senior High School before matriculating at Pembroke College in Brown University in 1961. At Pembroke, Buc participated in student life and served on the Student Government Association, including a term as president. Buc graduated in the class of 1965 with an A.B. in American Civilization. She went on to earn an LL.B. degree from the University of Virginia School of Law in 1969. Buc began her legal career as an attorney with the Federal Trade Commission in 1969. In 1972, Buc joined the law firm Weil, Gotshal and Manges. She was the firm's first woman partner, remaining at the firm until becoming Chief Counsel for the United States Food and Drug Administration from 1980 to 1981. In 1981, Buc returned to Weil, Gotshal and Manges and stayed there until 1994. She then left to co-found with attorney Kate Beardsley the Washington, DC law firm Buc and Beardsley. Buc retired from practicing law on March 31, 2011 at the age of 66.