Mary Meeker, a venture capitalist at Kleiner Perkins, plans to depart the firm in 2018 to start a new investment fund. It is a significant loss for Kleiner, which hired Ms. Meeker, a former Wall Street analyst known as the Queen of the Internet for her bullish coverage of internet stocks, in 2010. Ms. Meeker and her partners plan to invest in mature technology start-ups, with the potential to seek more deals outside the United States. She and her partners will also continue to invest money from Kleiner’s KPCB Digital Growth Fund III, a $1 billion vehicle, Kleiner said. More than half of the money in the fund has been deployed into start-ups. Mary focuses on investments in KPCB’s digital practice and helps lead the Digital Growth Fund, targeting high-growth Internet companies that have achieved rapid adoption and scale. She serves on the boards of Square, Lending Club, DocuSign and Quirky. Mary previously worked at Morgan Stanley and served as managing director and research analyst. Since beginning her career as a securities analyst in 1986, Mary has focused on discovering and understanding emerging technology trends, building relationships with visionary entrepreneurs and supporting category-defining companies.