PSI is a leading global health organization with programs targeting malaria, child survival, HIV and reproductive health. Working in partnership within the public and private sectors, and harnessing the power of the markets, PSI provides life-saving products, clinical services and behavior change communications that empower the world's most vulnerable populations to lead healthier lives. PSI was founded in 1970 to improve reproductive health using commercial marketing strategies. For its first 15 years, PSI worked mostly in family planning (hence the name Population Services International). In 1985, it started promoting oral rehydration therapy. PSI’s first HIV prevention project — which promoted abstinence, fidelity and condoms — began in 1988. PSI added malaria and safe water to its portfolio in the 1990s and tuberculosis in 2004. PSI has an uncommon focus on measurable health impact and attempts to measure its effect on disease and death much like a for-profit measures its profits. In 2007, PSI estimates that its programs directly prevented more than 156,000 HIV infections, 2.6 million unintended pregnancies, almost 150,000 deaths from malaria and diarrhea and 19 million malaria episodes. In addition, roughly 25,000 patients were treated for TB. World headquarters in Washington, D.C., programs in more than 65 countries, European office in Amsterdam. More than 150 U.S. staff, more than 100 overseas expatriate staff and almost 8,000 local PSI affiliate staff.