Brian O'Dwyer (born October 10, 1945) is an American lobbyist and lawyer. He is the son of prominent New York lawyer, Paul O'Dwyer, and nephew of Mayor William O'Dwyer. He is married to the former Marianna Page MacWilliam, the former Associate Vice Chancellor of the State University of New York, with whom he has two children, Brendan Keith O’Dwyer and Kathleen Page O’Dwyer, and they have four grandchildren: Paul Ellis O’Dwyer, Patrick Trescott O’Dwyer, Reilly Page O’Dwyer, and Hailey Grace O’Dwyer. O'Dwyer was appointed the Commissioner of the United States National Commission of UNESCO by United States Secretary of State Hillary Clinton.