Moore had originally intended to return to Clanton and take over the family bank, People's Savings Bank, the largest bank in town, which had been founded by his great-grandfather in 1903. After Jack's graduation, the Moores moved to Indianapolis, where Jack served for six months as a captain in the Adjutant General Corps to satisfy his military obligation. When Jack was discharged, the Moores settled in Memphis, where he joined Martin Tate Morrow & Marston. He moved to Wildman Harrold Allen Dixon and McDonnell in 1977, and there he quickly formed the professional connection with Ben Rawlins , then president of Memphis-based Union Planters Bank, that would make his career. Rawlins had asked Moore to join the Union Planters board of directors soon after he was named CEO of Union Planters in 1984, a role for which Moore was well-qualified; he was a major shareholder in his family's Clanton, Alabama, bank, and also sat on the board of a holding company for two Arkansas banks owned by his father-in-law. When Rawlins also became chairman of the Union Planters' board in 1989, he asked Moore to join Union Planters Corporation as its president. When Rawlins died suddenly and unexpectedly at age 61 of a heart attack on September 13, 2000, Moore felt the loss keenly even as he stepped into the role of chairman and CEO. In 2004, Moore guided Union Planters through a merger with Birmingham, Alabama-based Regions Financial Corporation. He retired in 2007, but remains on the board of the family-owned bank in Clanton, Alabama. In retirement, Moore stepped down from corporate boards with the exception of those of companies in which he owned an interest, but continues to serve on the boards of several non-profits, including the Methodist LaBonheur Healthcare network in Memphis and the RISE Foundation as well as on the President's Cabinet at the University of Alabama, which he has chaired since 2009.